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Collection of Teaching Resources

Teaching Resource: STAMINA CELLS - HLA

Subject taught
- Biology


Type of Product
- Videos

Language Skills Developed
- Listening
- Reading

Transferable/Scientific Skills Developed
The student must demonstrate knowledge and understanding of the problems relating to the fundamental concepts of tissue compatibility.

General aims The main purpose of this resource is to understand the fundamental role played by the HLA system for transplants. In fact, if the transplanted tissue in a subject is not HLA-compatible (i.e. its cells do not have the same HLA antigens as the recipient), the transplant is recognized as foreign and rejected. For this reason, before performing a transplant, it is of primary importance to ascertain that donor and recipient are HLA-compatible. As well as in the field of organ and tissue transplantation, the molecules of the HLA system are of fundamental importance in the mechanisms of immunological recognition of all foreign substances that come into contact with the organism. Linguistic aims • Improving language skills in L2 • Enriching scientific vocabulary • Knowing how to move from one linguistic register to another • Producing clear and coherent texts in L2 • Summarizing written texts Subject specific aims • To understand tissue compatibility; • to understand the role of HLA in the recognition of an antigen; • to understand the different functions performed by the class I, II and III MHC genes in humans; Target group age 15-16 years Level of competence in English (CEFR) B1 Time required to use the resource with the students 3h 2h first resource analysis 1h comparison and discussion How to use it (Prerequisiti: concetti base del sistema immunitario) (Prerequisites: basic concepts of the immune system) The teacher briefly recalls the basic concepts of immunity and then introduces the resource, highlighting the importance of the function performed by the HLA and the link between this complex and the action of the immune system. Therefore, students divided into small groups face the analysis and study of the resource. To facilitate understanding of the video, it is divided into shorter parts that students must study and, if necessary, deepen. In addition, to facilitate understanding of the topic, various exercises are proposed such as questionnaires with true / false answer, multiple choice, open questions, answer questions, completion of sentences, association of terms, keywords, use of certain words to compose sentences . During the meeting with the other groups, each group will have to present a short work on what has been studied, work that can be done through slides, videos, animations, etc., in order to also enhance their digital skills. It will then be included in the final work which will cover the entire learning unit and will be presented to different classes Possible difficulties for the students From a linguistic point of view, the resource does not present great difficulties, while understanding the topic can be a little difficult. Therefore, the teacher must be more present in guiding students in the study of this resource, he must provide explanations, insights and pay attention to the material produced by the boys.

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